Functional Genomics Approaches to Elucidate Vulnerabilities of Intrinsic and Acquired Chemotherapy Resistance

Drug resistance is a generally unavoidable consequence of most cancers remedy that leads to remedy failure and illness relapse. Intrinsic (pre-existing) or acquired resistance mechanisms might be drug-specific or be relevant to a number of medication, leading to multidrug resistance. The presence of drug resistance is, nevertheless, tightly coupled to modifications in mobile homeostasis, which may result in resistance-coupled vulnerabilities. Unbiased gene perturbations by way of RNAi and CRISPR applied sciences are invaluable instruments to determine genotype-to-phenotype relationships on the genome scale. Furthermore, their software to most cancers cell traces can uncover new vulnerabilities which might be related to resistance mechanisms. Right here, we focus on focused and unbiased RNAi and CRISPR efforts within the discovery of drug resistance mechanisms by specializing in first-in-line chemotherapy and their enforced vulnerabilities, and we current a view ahead on which measures ought to be taken to speed up their medical translation.

With a lot genomics information being produced, it is likely to be sensible to pause and think about what goal this information can or ought to serve. Some enhance annotations, others predict molecular interactions, however few add on to current data. It is because sequence annotations don’t all the time implicate perform, and molecular interactions are sometimes irrelevant to a cell’s or organism’s survival or propagation. Merely correlative relationships present in massive information fail to supply solutions to the Why questions of human biology. As a substitute, these solutions are anticipated from strategies that causally hyperlink DNA modifications to downstream results with out being confounded by reverse causation.

These approaches require the managed measurement of the implications of DNA variants, for instance, both these launched in single cells utilizing CRISPR/Cas9 genome enhancing or which might be already current throughout the human inhabitants. Inferred causal relationships between genetic variation and mobile phenotypes or illness present promise to quickly develop and underpin our data base.

Molecular and Structural Characterizations of Lipases from Chlorella by Purposeful Genomics

Microalgae have been poorly investigated for new-lipolytic enzymes of biotechnological curiosity. In silico research combining evaluation of sequences homologies and bioinformatic instruments allowed the identification and preliminary characterization of 14 putative lipases expressed by Chlorella vulagaris. These proteins have totally different molecular weights, subcellular localizations, low instability index vary and not less than 40% of sequence id with different microalgal lipases.

Sequence comparability indicated that the catalytic triad corresponded to residues Ser, Asp and His, with the nucleophilic residue Ser positioned inside the consensus GXSXG pentapeptide. 3D fashions had been generated utilizing totally different approaches and templates and demonstrated that these putative enzymes share an identical core with widespread α/β hydrolases fold belonging to household three lipases and sophistication GX. Six lipases had been predicted to have a transmembrane area and a lysosomal acid lipase was recognized. The same mammalian enzyme performs an essential function in breaking down cholesteryl esters and triglycerides and its deficiency causes critical digestive issues in human. Extra structural perception would supply essential info on the enzyme traits.

The specificity between pathotypes of Pyricularia oryzae and genera of gramineous crops is ruled by gene-for-gene interactions. Right here, we present that avirulence genes concerned on this host specificity have undergone totally different modes of purposeful losses depending on, or affected by genomic compartments harboring them. The avirulence of an Eleusine pathotype on wheat is managed by 5 genes together with PWT3 which performed a key function within the evolution of the Triticum pathotype (the wheat blast fungus). We cloned one other gene utilizing an affiliation of its presence/absence with pathotypes, and designated it as PWT6. PWT6 was broadly distributed in a lineage composed of Eleusine/Eragrostis isolates, however fully absent in a lineage composed of Lolium/Triticum isolates.

Functional Genomics Approaches to Elucidate Vulnerabilities of Intrinsic and Acquired Chemotherapy Resistance

Genomic and purposeful analyses of fungal and bacterial consortia that allow lignocellulose breakdown in goat intestine microbiomes

The herbivore digestive tract is house to a posh group of anaerobic microbes that work collectively to interrupt down lignocellulose. These microbiota are an untapped useful resource of strains, pathways and enzymes that might be utilized to transform plant waste into sugar substrates for inexperienced biotechnology. We carried out greater than 400 parallel enrichment experiments from goat faeces to find out how substrate and antibiotic choice affect membership, exercise, stability and chemical productiveness of herbivore intestine communities. We assembled 719 high-quality metagenome-assembled genomes (MAGs) which might be distinctive on the species stage. Greater than 90% of those MAGs are from beforehand unidentified herbivore intestine microorganisms. Microbial consortia dominated by anaerobic fungi outperformed bacterially dominated consortia by way of each methane manufacturing and extent of cellulose degradation, which signifies that fungi have an essential function in methane launch.

ICP Multi Elem (8) Std in 2% HNO3
ICP-MIX8	Scientific Laboratory Supplies	250ML	EUR 338.58

ICP-MS Multi-Element Solution 2
CLMS-2	Scientific Laboratory Supplies	125ML	EUR 399

ICP-MS Multi-Element Solution 3
CLMS-3	Scientific Laboratory Supplies	125ML	EUR 524.4

ICP-MS Multi-Element Solution 4
CLMS-4	Scientific Laboratory Supplies	125ML	EUR 221.16

ICP-MS Multi-Element Solution 5
CLMS-5	Scientific Laboratory Supplies	125ML	EUR 156.18

ICP Multi Elem (18) Std 5% HNO3
ICP18-MIX-2	Scientific Laboratory Supplies	1L	EUR 1687.2

ICP-MS Alternate Internal Standard 2
CL-ISM2-100	Scientific Laboratory Supplies	125ML	EUR 345.42

ICP Multi Elem (6) Std in 2% HNO3 100ppm
ICP-MUL06	Scientific Laboratory Supplies	100ML	EUR 201.78

ICP Multi Elem (18) Std in 5%
ICP-JM-ME10A	Scientific Laboratory Supplies	500ML	EUR 498.18

5 Component Mix
AOAC-MIX-1	Scientific Laboratory Supplies	EACH	EUR 117.42

ICP Multi Elem (11) Std in 2% HCl
ICP11-MIX-100	Scientific Laboratory Supplies	100ML	EUR 456

ICP Multi Elem (13) Std in 2% HNO3
ICP13-MIX-100	Scientific Laboratory Supplies	100ML	EUR 485.64

ICP Multi Elem (5) Std 100mg/L in 2% HNO3
ICP-MIX2	Scientific Laboratory Supplies	125ML	EUR 190.38

ICP Multi Elem (12) Std in 5% HNO3
ICP-CA-12C1	Scientific Laboratory Supplies	100ML	EUR 381.9

ICP Multi Elem (18) Std in 5% HCl
ICP-JM-ME4A	Scientific Laboratory Supplies	500ML	EUR 588.24

ICP Multi Elem (16) Std in 5% HNO3
ICP-LAN16-100	Scientific Laboratory Supplies	100ML	EUR 679.44

ICP Multi Elem (18) Std in 2% HNO3
ICP-MIX1-CYM	Scientific Laboratory Supplies	100ML	EUR 297.54

ICP Multi Elem (8) Std in 2% HNO3
ICP-MUL8-250ML	Scientific Laboratory Supplies	250ML	EUR 1144.56

ICP Multi Elem (9) Std in 1.2% HN03
ICP-SL-SOLN1	Scientific Laboratory Supplies	250ML	EUR 338.58

ICP Multi Elem (8) Std in 0.1% HNO3
ICP-TG-85	Scientific Laboratory Supplies	500ML	EUR 283.86

ICP Multi Elem (5) Std in 2% HNO3
ICP-VL-51	Scientific Laboratory Supplies	100ML	EUR 413.82

ICP Multi Elem (9) Std in 2% HNO3
ICP-WY-95	Scientific Laboratory Supplies	500ML	EUR 444.6

ICP Multi Elem (8) Std 100 mg/L in 2% HNO3
ICP-MUL8	Scientific Laboratory Supplies	100ML	EUR 289.56

ICP-MS Instrument Calibration Standard 1
CL-CAL-1	Scientific Laboratory Supplies	125ML	EUR 360.24

ICP-MS Instrument Check Standard 1
CL-ICS-1	Scientific Laboratory Supplies	125ML	EUR 315.78

ICP Multi Elem (8) Std in 2% HNO3 1000ppm
ICP-SC-851	Scientific Laboratory Supplies	500ML	EUR 613.32

ICP Multi Elem (4) Std in 2.5% of Glucose
ICP-SDHT-401	Scientific Laboratory Supplies	100ML	EUR 235.98

ICP Multi Elem (9) Std 10ppm in 1.2% HN03
ICP-SL-SOLN2	Scientific Laboratory Supplies	250ML	EUR 338.58

ICP-MS Set of 7 Multi-Element Solutions
CLMS-SET	Scientific Laboratory Supplies	EACH	EUR 1344.06

ICP Multi Elem (4) Std in 10% HNO3
ICP-THE-4-100	Scientific Laboratory Supplies	100ML	EUR 254.22

Internal Standard
5022-I	Scientific Laboratory Supplies	1ML	EUR 27.36

Internal Standard
507-I	Scientific Laboratory Supplies	1ML	EUR 137.94

Internal Standard
5252-I	Scientific Laboratory Supplies	1ML	EUR 69.54

Internal Standard
624-I	Scientific Laboratory Supplies	1ML	EUR 28.5

Internal Standard
8260-I	Scientific Laboratory Supplies	1ML	EUR 37.62

Internal Standard
CLPS-I	Scientific Laboratory Supplies	1ML	EUR 98.04

ICP Multi Elem (19) Std 100ppm in 2-5% HNO3
ICP-HR-195	Scientific Laboratory Supplies	500ML	EUR 793.44

ICP Multi Elem (2) Std Si S 100ppm in H2O
ICP-HR-25	Scientific Laboratory Supplies	500ML	EUR 158.46

ICP Multi Elem (4) Std in 5% HNO3 + 0.5% HF
ICP-MIX2-CYM	Scientific Laboratory Supplies	100ML	EUR 190.38

ICP Multi Elem (5) Std in 2% HNO3 1000ug/mL
ICP-MIX3-CYM	Scientific Laboratory Supplies	100ML	EUR 190.38

ICP Multi Elem (3) Std in 5% HNO3 + 0.5% HCl
ICP-PS-325M	Scientific Laboratory Supplies	250ML	EUR 360.24

ICP Multi Elem (2) Std 1000ppm Sn Ti in HCL
ICP-SC-25	Scientific Laboratory Supplies	500ML	EUR 224.58

ICP Multi Elem (10) Std in 10% HCl 10ug/mL
ICP-STD3-100	Scientific Laboratory Supplies	100ML	EUR 217.74

ICP-MS Initial Calibration Verification Standard 1
CL-ICV-1	Scientific Laboratory Supplies	125ML	EUR 371.64

ICP Multi Elem (10) Std in 2% HNO3 1000ppm
ICP-10-1000-100	Scientific Laboratory Supplies	100ML	EUR 392.16

Internal Standard Endosulfan-1
548-IS	Scientific Laboratory Supplies	1ML	EUR 37.62

ICP Multi Elem (3) Std 100ppm in 2-5% HNO3 + HF
ICP-HR-35	Scientific Laboratory Supplies	500ML	EUR 213.18

ICP Multi Elem (3) Std P S Si 1000ppm in Water
ICP-SC-35	Scientific Laboratory Supplies	500ML	EUR 338.58

ICP Multi Elem (13) Std 1000ppm in 2-5% HNO3 + HF
ICP-STL-136	Scientific Laboratory Supplies	500ML	EUR 633.84

Qual Set ICP Multi-Element (7) 1ppm to 1000ppm
AQSICP001	Scientific Laboratory Supplies	100ML	EUR 1194.72

Qual Set ICP Multi-Element (19) 1ppm to 1000ppm
AQSICP002	Scientific Laboratory Supplies	100ML	EUR 2566.14

ICP Multi Elem (10) Std in 1% HCl
ICP10-STATION-1	Scientific Laboratory Supplies	100ML	EUR 438.9

Aflatoxin MIX Standard
SD009	Unibiotest	0.5ug/mL	EUR 728.4

ICP Multi Elem (4) Std Ni Pb V Zn 1000ppm in HNO3
ICP-SC-45	Scientific Laboratory Supplies	500ML	EUR 380.76

ICP Multi Elem (9) Std in 2% HNO3 100mg/L
ICP-MET-9-100	Scientific Laboratory Supplies	100ML	EUR 337.44

Internal Standard R46594
50R-R46594	Fitzgerald	50 mg	EUR 289.2
Description: Internal standard 3-(2-[4-(4-chlorobenzyl)-1-piperidinyl]ethyl)-2,4-[1h,3H]-quinazoline-dione (R46594)

Itraconazole Internal Standard
50R-R51012	Fitzgerald	50 mg	EUR 289.2
Description: Itraconazole chemical reference substance

Internal Standard Pentachloronitrobenzene
508-I	Scientific Laboratory Supplies	1ML	EUR 128.82

Internal Standard Fluorobenzene
5242-I	Scientific Laboratory Supplies	1ML	EUR 39.9

Internal Standard Bromofluorobenzene
5511-I	Scientific Laboratory Supplies	1ML	EUR 102.6

Internal/Surrogate Standard
601-I	Scientific Laboratory Supplies	1ML	EUR 69.54

Alternate Internal Standard
8260A-I	Scientific Laboratory Supplies	1ML	EUR 42.18

Internal Standard 2mL
CLPS-I2	Scientific Laboratory Supplies	2ML	EUR 102.6

Alternate Internal Standard
CLPS-I90	Scientific Laboratory Supplies	1ML	EUR 51.3

Internal Standard 2
CLPV-I2	Scientific Laboratory Supplies	1ML	EUR 36.48

Volatile Organics Mix
60-BIG-MIX	Scientific Laboratory Supplies	1ML	EUR 120.84

ICP Multi Elem (3) Std Ag Hg Tl 10 mg/L in 2% HNO3
ICP-PC-35A	Scientific Laboratory Supplies	500ML	EUR 380.76

ICP Multi Elem (3) Std B P S 100mg/L in H2O
ICP-INT-3-500	Scientific Laboratory Supplies	500ML	EUR 265.62

Semi-volatile Organics Mix
76-BIG-MIX	Scientific Laboratory Supplies	1ML	EUR 150.48

ICP Standard Phosphorus H2O
PP2A7	Scientific Laboratory Supplies	100ML	EUR 177.84

ICP Multi Elem (4) Std in 7% HCl Sn Au Pd Rh 1ppm
ICP-LX-4-25	Scientific Laboratory Supplies	250ML	EUR 582.54

ICP Multi Elem (3) Std in 2% HCl Hg Ca Mg 100mg/L
ICP-MET-3-100	Scientific Laboratory Supplies	100ML	EUR 120.84

Internal Standard-3 Components
5243-I	Scientific Laboratory Supplies	1ML	EUR 172.14

Internal Standard Acenapthene-d10
5481-IS	Scientific Laboratory Supplies	1ML	EUR 128.82

Internal Standard 44-Difluorobiphenyl
550-I	Scientific Laboratory Supplies	1ML	EUR 50.16

Alternate Internal/Surrogate Standard
8082-I	Scientific Laboratory Supplies	1ML	EUR 106.02

Assurance Grade Set of 38 Single-Element Standards 1000 ug/mL (1000 PPM)
ICP-KIT-1	Scientific Laboratory Supplies	EACH	EUR 1914.06

Volatile Organics Mix (76 Components)
8260-BIG-MIX	Scientific Laboratory Supplies	1ML	EUR 296.4

PIANO DHA Standard Mix 1 45 compounds
REPIANO1	Scientific Laboratory Supplies	1ML	EUR 630.42

Individual Reaction Mix 1
G065-1	ABM	200 reactions	EUR 200.4

dNTP Mix (1 ml)
9002-1	Biovision	each	EUR 183.6

ICP Interference Check Standard 5
INTER5-100	Scientific Laboratory Supplies	125ML	EUR 228

ICP Interference Check Standard 5
INTER5-500	Scientific Laboratory Supplies	500ML	EUR 388.74

ICP Standard Beryllium 2-5pc
PBE2A2	Scientific Laboratory Supplies	100ML	EUR 132.24

ICP Standard Manganese 2-5pc
PMN2A2	Scientific Laboratory Supplies	100ML	EUR 95.76

ICP Standard Strontium 2-5pc
PSR2A2	Scientific Laboratory Supplies	100ML	EUR 177.84

ICP Standard Vanadium 2pc HNO3
PV2A19	Scientific Laboratory Supplies	100ML	EUR 136.8

ICP Standard Zinc 2pc HCl
PZN2A3	Scientific Laboratory Supplies	100ML	EUR 95.76

ICP Quality Control Standard 21
QC-21	Scientific Laboratory Supplies	125ML	EUR 337.44

ICP Quality Control Standard 21
QC-21-250	Scientific Laboratory Supplies	250ML	EUR 454.86

ICP Quality Control Standard 21
QC-21-500	Scientific Laboratory Supplies	500ML	EUR 549.48

ICP Quality Control Standard 22
QC-22	Scientific Laboratory Supplies	125ML	EUR 473.1

ICP Quality Control Standard 22
QC-22-250	Scientific Laboratory Supplies	250ML	EUR 514.14

ICP Quality Control Standard 22
QC-22-500	Scientific Laboratory Supplies	500ML	EUR 615.6

ICP Quality Control Standard 23
QC-23	Scientific Laboratory Supplies	125ML	EUR 527.82

ICP Quality Control Standard 24
QC-24	Scientific Laboratory Supplies	125ML	EUR 473.1

ICP Quality Control Standard 7
QC-7	Scientific Laboratory Supplies	125ML	EUR 176.7

ICP Quality Control Standard 7
QC-7-500	Scientific Laboratory Supplies	500ML	EUR 290.7

ICP Quality Control Standard 7A
QC-7A	Scientific Laboratory Supplies	125ML	EUR 169.86

ICP Qualicty Control Standard 7A
QC-7A-500	Scientific Laboratory Supplies	500ML	EUR 281.58

ICP Instrument Check Standard 10
CALMIX10-100	Scientific Laboratory Supplies	125ML	EUR 175.56

ICP Instrument Check Standard 10
CALMIX10-500	Scientific Laboratory Supplies	500ML	EUR 297.54

ICP Instrument Check Standard 3
CALMIX3-100	Scientific Laboratory Supplies	125ML	EUR 210.9

ICP Instrument Check Standard 3
CALMIX3-500	Scientific Laboratory Supplies	500ML	EUR 343.14

ICP Instrument Check Standard 4
CALMIX4-100	Scientific Laboratory Supplies	125ML	EUR 223.44

ICP Instrument Check Standard 4
CALMIX4-500	Scientific Laboratory Supplies	500ML	EUR 363.66

ICP Instrument Check Standard 7
CALMIX7-100	Scientific Laboratory Supplies	125ML	EUR 264.48

ICP Instrument Check Standard 7
CALMIX7-500	Scientific Laboratory Supplies	500ML	EUR 461.7

ICP Instrument Check Standard 8
CALMIX8-500	Scientific Laboratory Supplies	500ML	EUR 285

ICP-MS Calibration Standard 3
CL-CAL-3	Scientific Laboratory Supplies	125ML	EUR 121.98

Internal Standard for GC/FID
8015B-I	Scientific Laboratory Supplies	1ML	EUR 83.22

ASTM Method D6042 Internal Standard
ASTM-D6042-IS	Scientific Laboratory Supplies	1ML	EUR 320.34

Organic Wine Standard 1
WINE-1	Scientific Laboratory Supplies	1ML	EUR 141.36

Volatile Organics Mix (Low Level)
60-BIG-MIX-200	Scientific Laboratory Supplies	1ML	EUR 116.28

Volatile Organics Mix (High Level)
60-BIG-MIX-2000	Scientific Laboratory Supplies	1ML	EUR 165.3

ICP Multi Elem (10) Std in 1% HCl
ICP10-STATION-2	Scientific Laboratory Supplies	100ML	EUR 438.9

Multi-element stand with lab jack
HOM2548	Scientific Laboratory Supplies	EACH	EUR 647.52

Aromatics Calibration Standard (18 Component Mix)
NJDEP-EPH-ARCS	Scientific Laboratory Supplies	1ML	EUR 91.2

IC Multi Elem (6) Anion Std in H2O
ICA6-MIX-THG	Scientific Laboratory Supplies	100ML	EUR 269.04

Metabolic pathway reconstructions from MAGs of 737 micro organism, archaea and fungi recommend that cross-domain partnerships between fungi and methanogens enabled manufacturing of acetate, formate and methane, whereas bacterially dominated consortia primarily produced short-chain fatty acids, together with propionate and butyrate. Analyses of carbohydrate-active enzyme domains current in every anaerobic consortium recommend that anaerobic micro organism and fungi make use of principally complementary hydrolytic methods. The division of labour amongst herbivore anaerobes to degrade plant biomass might be harnessed for industrial bioprocessing.

Functional Genomics Approaches to Elucidate Vulnerabilities of Intrinsic and Acquired Chemotherapy Resistance

Molecular and Structural Characterizations of Lipases from Chlorella by Purposeful Genomics

Genomic and purposeful analyses of fungal and bacterial consortia that allow lignocellulose breakdown in goat intestine microbiomes

ICP Multi Elem (8) Std in 2% HNO3

ICP-MS Multi-Element Solution 2

ICP-MS Multi-Element Solution 3

ICP-MS Multi-Element Solution 4

ICP-MS Multi-Element Solution 5

ICP Multi Elem (18) Std 5% HNO3

ICP-MS Alternate Internal Standard 2

ICP Multi Elem (6) Std in 2% HNO3 100ppm

ICP Multi Elem (18) Std in 5%

5 Component Mix

ICP Multi Elem (11) Std in 2% HCl

ICP Multi Elem (13) Std in 2% HNO3

ICP Multi Elem (5) Std 100mg/L in 2% HNO3

ICP Multi Elem (12) Std in 5% HNO3

ICP Multi Elem (18) Std in 5% HCl

ICP Multi Elem (16) Std in 5% HNO3

ICP Multi Elem (18) Std in 2% HNO3

ICP Multi Elem (8) Std in 2% HNO3

ICP Multi Elem (9) Std in 1.2% HN03

ICP Multi Elem (8) Std in 0.1% HNO3

ICP Multi Elem (5) Std in 2% HNO3

ICP Multi Elem (9) Std in 2% HNO3

ICP Multi Elem (8) Std 100 mg/L in 2% HNO3

ICP-MS Instrument Calibration Standard 1

ICP-MS Instrument Check Standard 1

ICP Multi Elem (8) Std in 2% HNO3 1000ppm

ICP Multi Elem (4) Std in 2.5% of Glucose

ICP Multi Elem (9) Std 10ppm in 1.2% HN03

ICP-MS Set of 7 Multi-Element Solutions

ICP Multi Elem (4) Std in 10% HNO3

Internal Standard

Internal Standard

Internal Standard

Internal Standard

Internal Standard

Internal Standard

ICP Multi Elem (19) Std 100ppm in 2-5% HNO3

ICP Multi Elem (2) Std Si S 100ppm in H2O

ICP Multi Elem (4) Std in 5% HNO3 + 0.5% HF

ICP Multi Elem (5) Std in 2% HNO3 1000ug/mL

ICP Multi Elem (3) Std in 5% HNO3 + 0.5% HCl

ICP Multi Elem (2) Std 1000ppm Sn Ti in HCL

ICP Multi Elem (10) Std in 10% HCl 10ug/mL

ICP-MS Initial Calibration Verification Standard 1

ICP Multi Elem (10) Std in 2% HNO3 1000ppm

Internal Standard Endosulfan-1

ICP Multi Elem (3) Std 100ppm in 2-5% HNO3 + HF

ICP Multi Elem (3) Std P S Si 1000ppm in Water

ICP Multi Elem (13) Std 1000ppm in 2-5% HNO3 + HF

Qual Set ICP Multi-Element (7) 1ppm to 1000ppm

Qual Set ICP Multi-Element (19) 1ppm to 1000ppm

ICP Multi Elem (10) Std in 1% HCl

Aflatoxin MIX Standard

ICP Multi Elem (4) Std Ni Pb V Zn 1000ppm in HNO3

ICP Multi Elem (9) Std in 2% HNO3 100mg/L

Internal Standard R46594

Itraconazole Internal Standard

Internal Standard Pentachloronitrobenzene

Internal Standard Fluorobenzene

Internal Standard Bromofluorobenzene

Internal/Surrogate Standard

Alternate Internal Standard

Internal Standard 2mL

Alternate Internal Standard

Internal Standard 2

Volatile Organics Mix

ICP Multi Elem (3) Std Ag Hg Tl 10 mg/L in 2% HNO3

ICP Multi Elem (3) Std B P S 100mg/L in H2O

Semi-volatile Organics Mix

ICP Standard Phosphorus H2O

ICP Multi Elem (4) Std in 7% HCl Sn Au Pd Rh 1ppm

ICP Multi Elem (3) Std in 2% HCl Hg Ca Mg 100mg/L

Internal Standard-3 Components

Internal Standard Acenapthene-d10

Internal Standard 44-Difluorobiphenyl

Alternate Internal/Surrogate Standard

Assurance Grade Set of 38 Single-Element Standards 1000 ug/mL (1000 PPM)